Bile Acids for Aqua

Bile Acids Enabling Innovation:The 13th SWCSNFFS (II)


5.Microbial ingredients from blue and green biomass for aquafeeds

Prof.Margareth Overland

Professor, Norges miljø-og biovitenskapelige universitet NMBU


 Abstract of Speech:

The lignocellulose in the tree is pretreated into cellulose and hemicellulose, and then hydrolyzed by soluble polysaccharide monooxygenase to produce C5 and C6 sugars, and then enter the fermentation process, and then undergo centrifugal filtration and drying to produce feed yeast . In addition, seaweed is also a potential feed resource. Taking brown algae as an example, low-molecular components (such as sugars, nitrogen sources, minerals, etc.), high-molecular components (such as proteins), and biologically active components can be produced by yeast fermentation.

6. New approaches, techniques and tools in fish nutrition

Prof. Stephane Panserat




Abstract of Speech:

The current nutrition research has gradually developed from the specific effect of a single nutrient to the comprehensive evaluation of multiple nutrients and specific nutritional status. The research method has shifted from the analysis and identification of single molecules to the systematic assessment of metabolic status. Nutritionomics methods play an indispensable role in gene expression and metabolic network construction, biomarker selection analysis, health and physiological state assessment, etc.


7. The Fish diversity history and their genome resources in China


He Shunping 

Researcher,Institute of Hydrobiology, Chinese Academy of Sciences


Professor, Norges miljø-og biovitenskapelige universitet N

Abstract of Speech:

By selecting mitochondrial COI gene sequence fragments as markers, a DNA barcode database of Chinese freshwater fishes is constructed, and the established DNA barcode database is integrated with the running Chinese fish biodiversity database to establish Chinese freshwater fish species and corresponding DNA Comprehensive database linked to barcodes. Aims to establish a large-scale, high-quality fish genome database, focusing on fish genome research.

8. The theory and targeted modulation of dietary protein utilization in aquaculture


Prof.MargarHe Gen

Professor ,Ocean University of China

eth Overland

  Abstract of Speech:

Nutrition requirement is a variable, which changes with various factors such as growth stage, various elements of the breeding environment, and feed formula composition. Studies have found that mTOR is the key point for living organisms to sense nutrients and regulate growth and health. The activation degree of mTOR can accurately reflect the optimal protein requirements. Fish meal is the best protein source for activating mTOR in a single protein source. Substitution of fish meal will result in insufficient activation of mTOR, resulting in insufficient body protein synthesis, resulting in a decline in growth performance.

By adding vitamins, active peptides, amino acids, trace elements, and functional additives, such as bile acid, targeted regulation of mTOR aims to improve the growth rate, weight gain, economic benefits and other aspects of aquatic animals.

9. The effect of bile acids supplement in high plant protein feed on Common Carp (Cyprinus carpio) bile acids profile and liver health


Gu Xu 

Associate Professor,Feed Research Institute Chinese Academy of Agricultural Sciences



Abstract of Speech:

High plant protein feed can cause carp intestinal inflammation, induce the body's glucose and lipid metabolism disorder, and lead to metabolic fatty liver disease; by adding bile acids, it can enhance gluconeogenesis and lipolysis, improve the body's glucose and lipid metabolism, and activate ERK phosphorylation. Start self-repair, reduce inflammation, relieve liver and intestine damage and metabolic liver disease.

After the addition of bile acids, the carp bile acid spectrum changes sound, the content of TβMCA increases, which inhibits intestinal FXR, regulates glucose metabolism, and reduces glycogen accumulation; the content of GLCA, GHCA and glycine-bound bile acids increases, which plays an important role in the anti-inflammatory response Regulating effect, protect the liver from inflammatory factors.

10. Studies of the physiological efficacy and suitable supplementation levels of bile acid and cholesterol on Litopenaeus Vannamei


Su Chen

PhD,Ocean University of China



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